Novosibirsk Region is located in the center of Russia, in the southeast of the West-Siberian plain. The region borders with the Omsk Region in the west, Tomsk Region in the north, Kemerovo Region in the east, Altay Territory on the south, and Kazakhstan in the southwest.

Due to its geographical location, the region has continental climate. Winter here is rather cold and long with occasional strong winds and snowstorms. Average winter temperature in Novosibirsk is about –18-20C. The lowest temperature (-54C degrees) was registered here in 1938. Summer is hot (about 100-130 days). Average summer temperature is about +18+20C.