The "golden age" of Vladimir-Suzdal region was the 12th to 13th centuries. The principality was located between the Oka and Volga Rivers and extended as far north as Beloozero and Ustiug. Slavic settlers entered the region in the 10th century and soon made it the center of the Great Russian nation. The area is indeed the center, lying as it does across the river route from the Baltic Sea to the Caspian Sea via the Oka and Volga Rivers and adjacent to the route from the Baltic to the Black Sea via the Dnieper River.

Vladimir Region was founded on August 14th, 1944. Vladimir became the regional centre. It is located in the center of Russia European part and belongs to the central economic region of Russia. Vladimir Region encompasses 16 districts, 21 cities, 36 towns, and 222 villages.